Andreas Pfützner Selected Research

CNS 5161

7/2007

Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain.

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Andreas Pfützner Research Topics

Disease

65	Type 2 Diabetes Mellitus (MODY) 05/2020 - 01/2002
37	Insulin Resistance 05/2020 - 01/2003
15	Inflammation (Inflammations) 05/2020 - 02/2006
10	Hypoglycemia (Reactive Hypoglycemia) 01/2019 - 09/2007
10	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2015 - 05/2005
9	Diabetes Mellitus 03/2014 - 02/2006
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2017 - 01/2005
4	Pain (Aches) 01/2020 - 10/2004
4	Body Weight (Weight, Body) 11/2017 - 01/2005
4	Cardiovascular Diseases (Cardiovascular Disease) 05/2010 - 02/2006
4	Atherosclerosis 05/2010 - 03/2006
3	Obesity 04/2017 - 01/2003
3	Hyperglycemia 06/2015 - 01/2009
3	Weight Gain 11/2013 - 02/2006
3	Narcolepsy 01/2011 - 08/2007
2	Neoplasms (Cancer) 04/2017 - 10/2006
2	Mental Disorders (Mental Disorder) 08/2013 - 01/2010
2	Dyslipidemias (Dyslipidemia) 06/2011 - 03/2011
2	Turner Syndrome (Turner's Syndrome) 10/2010 - 10/2009
2	Hypertension (High Blood Pressure) 08/2007 - 07/2006
1	COVID-19 01/2022
1	Prediabetic State (Prediabetes) 05/2020
1	Weight Loss (Weight Reduction) 01/2017
1	Necrosis 01/2015
1	Fibrosis (Cirrhosis) 01/2015
1	Glucose Intolerance 01/2015
1	Diabetic Retinopathy (Retinopathy, Diabetic) 03/2014
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2014
1	Vision Disorders (Hemeralopia) 07/2012
1	Kidney Diseases (Kidney Disease) 01/2012
1	Renal Insufficiency (Renal Failure) 01/2012
1	Drug-Related Side Effects and Adverse Reactions 01/2012
1	Menorrhagia 09/2011
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2011
1	Circadian Rhythm Sleep Disorders (Delayed Sleep Phase Syndrome) 01/2011
1	Pruritus (Itching) 07/2010

Drug/Important Bio-Agent (IBA)

38	Insulin (Novolin)FDA Link 05/2020 - 01/2002
25	Pioglitazone (Actos)FDA Link 01/2012 - 01/2005
20	Glucose (Dextrose)FDA LinkGeneric 05/2020 - 01/2003
18	ProinsulinIBA 05/2020 - 01/2003
18	Biomarkers (Surrogate Marker)IBA 05/2020 - 01/2003
14	Blood Glucose (Blood Sugar)IBA 01/2020 - 04/2006
11	Metformin (Glucophage)FDA LinkGeneric 01/2015 - 03/2007
9	AdiponectinIBA 04/2017 - 03/2004
8	C-Reactive ProteinIBA 01/2015 - 01/2006
8	glimepiride (Amarel)FDA LinkGeneric 10/2014 - 10/2005
8	Hemoglobins (Hemoglobin)IBA 07/2012 - 12/2004
7	Hypoglycemic Agents (Hypoglycemics)IBA 05/2011 - 03/2006
5	Pharmaceutical PreparationsIBA 06/2009 - 10/2006
4	PPAR gammaIBA 11/2008 - 03/2006
4	PPAR-gamma AgonistsIBA 06/2008 - 01/2007
4	Rosiglitazone (Avandia)FDA Link 03/2007 - 01/2005
3	LipidsIBA 04/2017 - 01/2008
3	Insulin Glargine (Lantus)FDA Link 01/2017 - 05/2012
3	LinagliptinIBA 10/2014 - 01/2012
3	Retinaldehyde (Retinal)IBA 03/2014 - 01/2012
3	oxidized low density lipoproteinIBA 06/2011 - 11/2008
3	Insulin Lispro (Humalog)FDA Link 05/2011 - 05/2005
3	Simvastatin (Zocor)FDA LinkGeneric 01/2009 - 01/2007
3	ResistinIBA 03/2007 - 01/2003
2	Indicators and Reagents (Reagents)IBA 05/2020 - 06/2005
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 06/2015 - 08/2013
2	HDL LipoproteinsIBA 06/2011 - 06/2009
2	Triglycerides (Triacylglycerol)IBA 06/2011 - 06/2009
2	HDL CholesterolIBA 06/2011 - 06/2009
2	Short-Acting InsulinIBA 05/2011 - 06/2006
2	OrexinsIBA 01/2011 - 08/2007
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2010 - 01/2007
2	C-PeptideIBA 01/2009 - 01/2008
2	3-nitrotyrosineIBA 01/2009 - 07/2007
2	Nicotinamide PhosphoribosyltransferaseIBA 08/2008 - 03/2007
2	Biological ProductsIBA 08/2008 - 01/2005
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 05/2007 - 01/2007
1	MouthwashesIBA 01/2022
1	Xylose (D-Xylose)FDA Link 01/2017
1	Keratin-18 (Keratin 18)IBA 01/2015
1	K-18 conjugate (K18)IBA 01/2015
1	CollagenIBA 01/2015
1	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2015
1	CaspasesIBA 01/2015
1	lixisenatideIBA 11/2013
1	Glucagon-Like Peptide 1 (GLP 1)IBA 11/2013
1	VildagliptinIBA 04/2013
1	L 644711 (B-3(+))IBA 07/2012
1	2-mercaptopurineIBA 01/2012
1	Peptide Hydrolases (Proteases)FDA Link 07/2011
1	Ramipril (Altace)FDA LinkGeneric 07/2011
1	LDL Lipoproteins (beta Lipoproteins)IBA 06/2011
1	InsulinsIBA 05/2011
1	CD40 Ligand (CD40L)IBA 03/2011
1	ThromboxanesIBA 03/2011
1	Hormones (Hormone)IBA 01/2011
1	Growth Hormone (Somatotropin)IBA 10/2010

Therapy/Procedure

13	Therapeutics 01/2016 - 03/2004
8	Glycemic Control 06/2015 - 01/2005
5	Injections 12/2013 - 06/2006
2	Self-Testing 01/2020 - 09/2007
2	Renal Dialysis (Hemodialysis) 01/2012 - 09/2011
1	Punctures 04/2017
1	Catheters 07/2010